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UEL: The Innovation Hub Powering Minnesota’s Startup Future

Introduction by Sam Shuster, Executive Director, UEL and Full Stack Steering Committee Member

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Meet This Month's Featured Innovator

Sam is the new Executive Director of UEL. A PhD neuroscientist and lifelong entrepreneur, he brings a deep understanding of technology commercialization and firsthand experience starting and growing lab-based businesses. Sam has run and exited several businesses across multiple industries—from biotech to consumer electronics to his most recent venture commercializing novel automation equipment for the craft ice industry.

UEL is a 150,000 sq ft independent, mission-driven nonprofit incubator that is currently home to 60+ resident companies across biotech, medtech, agtech, and cleantech. UEL resident companies are working on solutions to some of our toughest challenges including eliminating PFAS from our environment, developing better biofuels, improving crop yield to help feed our planet, and cures to diseases that today are incurable.

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Photos provided by UEL

UEL occupies a unique role in Minnesota’s science and technology community by providing specialized, sophisticated lab space that would otherwise be cost-prohibitive for startups to build on their own. 

 

Over its two decades of operation, UEL has been home to 170 resident companies. Those companies have raised over $1.4 billion in capital, created approximately 2,000 jobs, and been granted over 1,500 patents.

 

Continue reading to see how UEL plans to expand in the future to help launch more start-ups.

Read Sam's Full Blog

Latest Tech and Innovation News

Grid Catalyst Introduces New Minnesota Utility Innovation Program

 

Grid Catalyst is launching GridReady – a new kind of utility innovation program that opens the door for the country's most promising energy startups to pilot their solutions with Minnesota's leading utilities.

 

Their utility partners – Great River Energy, Minnesota Power, Xcel Energy, and Otter Tail Power Company – are actively seeking new technologies to modernize the grid, keep energy reliable and affordable for their customers, and deliver on the state's ambitious commitment to 100% clean energy by 2040. Refer to the Startup Applicant Guide for more details on eligibility and selection criteria. Applications are open now and close June 26.

Take the Saint Paul Business Plan Survey

 

The City of Saint Paul invites Saint Paul business establishments to participate in a brief survey. The information you provide will help inform the policies intended to guide the City's economic growth and resilience in the coming years. This survey is being conducted on the behalf of the City of Saint Paul by TIP Strategies, an Austin-based economic strategy firm.

Ramsey County Launches Re-Imagination Resource Center

 

Ramsey County Community and Economic Development has launched the Re-Imagination Resource Center, a new initiative designed to strengthen the ability of local Business Community Organizations (BCOs) to better serve entrepreneurs and small businesses throughout Ramsey County, including Saint Paul. For small business owners in Saint Paul, the Re-Imagination Resource Center is intended to create more accessible pathways to business support and growth resources.

Local Tech & Workforce News Snapshots

Quick local hits you shouldn't miss.

  • Congratulations to Full Stack Steering Committee member Jamie Wascalus on being recognized for two awards: Minnesota ORBIE Award Finalist and Government Technology's Top 25 Doers, Dreamers and Drivers!

  • Macalester student Jolie Davis and Hallie Q. Brown Executive Director Benny Roberts, have created Rondo-Verse: a Roblox game featuring Saint Paul’s Rondo before and after I-94.

  • A lucrative sector: Twin Cities at center of life sciences boom. Read the full interview article from REJournals.

  • A geothermal pilot project at Macalester College in Saint Paul could illuminate a new way to heat and cool in cities using clean energy innovation.

  • This year’s Walleye Tank featured new backers, HealthcareMN. They hope to expand Walleye Tank throughout the Midwest over the next five years. Learn how HealthcareMN is impacting Minnesota's Healthcare AI Landscape in this feature from Executive Director Dr. Rashmi Kandwal.

  • Ecolab’s CEO is betting on an AI payoff and is looking to play a role in associated data centers and water and cooling innovation.

  • Pivot Bio, a billion-dollar company, relocated headquarters from California, choosing the Twin Cities over other Midwest cities.

  • At the University of Minnesota’s Wearable Technology Lab in Saint Paul, clothing becomes medical care for infants with jaundice.

Upcoming Events

Strengthen the Strong Luncheon

May 27 | 11:30 AM - 1:30 PM | Osborn370

 

Entrepreneurs' Rally XIV

May 27 | 7:45 AM - 2:30 PM | Union Depot

 

Open Source North

May 28 | 8:00 AM - 4:00 PM | University of St. Thomas

Sponsored by Full Stack Saint Paul

 

2026 Minnesota Immigrant Entrepreneurs Summit

June 5 | 8:30 AM - 3:30 PM | Minnesota Masonic Heritage Center

 

Live AI Agent Demo

June 11 | 2:00 - 3:30 PM | Nagios

 

Building Influence Through a YouTube Channel-Brought to you by Visit Saint Paul

June 18 | 2:00 - 3:00 PM | Virtual

View More Events

Need an Event Sponsor?

Hosting a tech event this year? Full Stack Saint Paul offers a limited number of event sponsorships each year for events that will benefit Saint Paul’s tech and innovation ecosystem. 

Submit Your Request

Full Stack Saint Paul is a public-private collaboration leveraging the power of tech and innovation to drive equitable, resilient economic development in Saint Paul.

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